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ISEV2017 Education Day

 

Education Day will take place on 17 May 2017.  Education Day will take place the Toronto Westin Harbour Castle Hotel, the same hotel as ISEV2017.  Education Day is a pre-conference event and requires registration.  Click here to register. 

 

Track A

EV Biology and Technology

Track B

EVs in Health and Disease

 

 

Timing

Talk

Timing

Talk

8.30-8.35

Welcome address

Susmita Sahoo

8.30-8.35

Welcome address

Janusz Rak

8.35-9.00

The rise of extracellular vesicle paradigm of cellular regulation

Clotilde Thery

8.35-9.00

Intro to EVs as biomarkers and therapeutics: Clinical advancements in EV

Edit Buzas

 

 

Block 1

Biology of EVs

Chair: Alissa Weaver

Block 1

Introduction to EV Analysis in Clinical Laboratory Settings

Chair: Dolores Di Vizio

9.00-9.20

Biogenesis of EVs and cargo selection: ESCRT-dependent and independent mechanisms

Stephen J. Gould

9.00-9.20

EV isolation for clinical application: How to handle body fluids, tissues and conditioned media

Louise Laurent

9.20-9.40

Uptake: interaction of EVs with recipient cells, membrane proteins

Dave Carter

9.20-9.40

Cell and tissue-specific EVs and EV sub-populations

Dolores Di Vizio

9.40-10.00

EV lipids and lipidomics

Juan M. Falcon-Perez

9.40-10.00

Production of EVs for therapeutic applications

Mario Gimona

10.00-10.30

Chaired Q and A discussion session with all three speakers

10.0-10.30

Chaired Q and A discussion session with all three speakers

 

 

10.30-10.50

Coffee break

10.30-10.50

Coffee break

 

 

Block 2

Isolation and Quantification: Methods and Challenges

Chair: Rienk Nieuwland

Block 2

EVs in Cancer

Janusz Rak

10.50-11.10

Differential centrifugation/density gradient/exoquick- Quality of isolation

An Hendrix

10.50-11.10

EVs in cancer establishment and progression

Xandra Breakefield

11.10-11.30

Microfluidics/size exclusion- quality of isolation

Hyungsoon Im

11.10-11.30

EVs in metastatic and tumour microenvironment

Andries Zijlstra

11.30-11.50

Standardization of nanoparticle measurements - NTA/qNano/DLS

Chris Gardiner

11.30-11.50

EVs as biomarkers and mediators of hemostasis and thrombosis

Nigel Mackman

11.50-12:20

Chaired Q and A discussion session with all four speakers

11.50-12:20

Chaired Q and A discussion session with all three speakers

 

 

12.20-1.20pm

Lunch break

12.20-1.20pm

Lunch break

 

 

Block 3

Characterization and Phenotyping

Chair: Alain Brisson

Block 3

Biomarkers and Pathological Mechanisms

Chair: Kenneth Witwer

1.20-1.40

High resolution flow cytometry

Joanne Lannigan

1.20-1.40

Overview of EV-driven pathological mechanisms

Vicky Yang

1.40-2.00

Surface molecules and vesicle cargo transfer

Alissa Weaver

1.40-2.00

EVs in cardio-renal diseases- RNA biomarkers?

Elena Aikawa

2.00-2.20

In vitro and in vivo labeling and trafficking: new techniques

Charles Lai

2.00-2.20

Where is the RNA in blood? Vesicles or free swimming?

Lesley Cheng

2.20-2.40

EV imaging: TEM/AFM/Confocal/Super resolution

Alain Brisson

2.20-2.40

Extracellular vesicles and viruses: Are they close relatives?

Kenneth Witwer

2.40-3.10

Chaired Q and A discussion session with all four speakers

2.40-3.10

Chaired Q and A discussion session with all speakers

 

 

3.10-3.30

Coffee break

3.10-3.30

Coffee break

 

 

Block 4

Advances in Profiling EV Content

Chair: Marca Wauben

Block 4

EVs in the Clinics: Challenges and Progress

Chair: Andrew Hill

3.30-3.50

Proteomics: EV enriched and non-EV enriched proteins

Simona Principe

3.30-3.50

Overview: Past, Present, Future of Therapeutic EVs

Jan Lotvall

3.50-4.10

RNA Seq: mRNA and small non-coding RNA

Esther Nolte-t Hoen

3.50-4.10

Stem cell derived EVs in regenerative medicine: Functional studies

Michael E. Davis

4.10-4.30

Computational deconvolution of EV cargo

Aleksandar Milosavjevic

4.10-4.30

EVs in Vaccine, Immunity, Drug Delivery, and Drug Resistance

Olga Volpert

4.30-4.50

Carriers of extracellular nucleic acids

Julie Saugstad

4.30-4.50

EVs in Neurodegeneration

Lawrence Rajendran

4.50-5.20

Chaired Q and A discussion session with all four speakers

4.50-5.20

Chaired Q and A discussion session with speakers

5.20-5.30

Wrap up

Marca Wauben

5.20-5.30

Wrap up

Andrew Hill

 

6:00-7:30pm: Satellite Session Title: “Emerging Trends in HIV, NeuroAIDS, Drug Abuse & EVs”

Chairs: Drs. Shilpa Buch and Fatah Kashanchi

6:00 – 6:10 pm: Opening Remarks by ISEV President - Andrew Hill, Ph.D., Director, La Trobe Institute for Molecular Sciences, Director, RFA Understanding Disease, Department of Biochemistry and Genetics, La Trobe University, Melbourne

6:10 - 6:20 pm: Shilpa Buch, Ph.D., Professor and Vice Chair for Research, Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center

Title: Tat and Opiates modulate HAND: Role of astrocyte derived exosomes

6:20 - 6:30 pm: Fatah Kashanchi, Ph.D., Professor, Laboratory of Molecular Virology, George Mason University; Director of Research, NCBID, School of Systems Biology

Title: Effect of anti-retroviral drugs on exosome production

6:30 - 6:40 pm: Kenneth W. Witwer, Ph.D., Assistant Professor, Department of Molecular and Comparative Pathobiology, Johns Hopkins University

Title: EVs, cigarettes, and HIV infection

6:40 - 6:50 pm: Coffee Break

6:50 - 7:00 pm: Lynn Pulliam, M.S., Ph.D., Professor, Chief, Microbiology (VAMC) Laboratory Medicine, Departments of Pathology & Laboratory Medicine, University of California, San Francisco

Title: Plasma neural-derived exosomes as biomarkers of cognitive impairment in HIV.

7:00 - 7:10 pm: Norman Haughey, Ph.D., Professor and Vice Chair for Research, Department of Neurology, Johns Hopkins University

Title: Deconstruction of Neural Networks by HIV-Associated Modifications in Exosome Cargo

7:10 - 7:20 pm: Vincent C. Bond, Ph.D., Professor and Chair of Microbiology, Biochemistry & Immunology, Morehouse School of Medicine; Director, Research Center in Minority Institutions (RCMI)

Title: HIV-1 Pathogenesis Hallmarks are Modulated by the Nef Secretion Modification Region

7:20 - 7:50 pm: Panel discussion moderated by Drs. Sowmya Yelamanchili and Guoku Hu

7:50 pm: Wrap Up