Inaugural Virtual Symposium on Urinary Extracellular Vesicles

We are pleased to announce that registration and abstracts are now open for the inaugural symposium on Urinary EVs!
 
This symposium will feature talks, lively discussions, and poster sessions. This is also an opportunity for the Urine Task Force of the Rigor and Standardization subcommittee of ISEV to give an update on their working groups. We hope to bring together a diverse group of uEV researchers that do not always have the opportunity to come together.
 
We are excited to have already two well known Keynote speakers who will set the stage for us: thank you to Dr. Guido Jenster from the Netherlands and Dr. Mark Knepper from the US. 

-The Urine Task Force of the ISEV Rigor and Standardization Subcommittee

 Registration is now closed.

Registrants received a Zoom link on Friday 11 February. Please send a message to [email protected] if you have not yet received the Zoom link.

Below is the program but also feel free to click on this link for the program and abstract book PDF. Please note the program is in Central European Time. Please click here to see what time it will be in your time zone. Last minute changes to the program may occur.

Presentation Start (CET) Presentation End (CET) Session Presentation Chairs Speaker Name
Tuesday 15 February 15
14:30 14:40
Welcome and Introduction to Urine Task Force
  Uta Erdbrügger and Charles Blijdorp Uta Erdbrügger and Charles Blijdorp
14:40 15:10 Keynote session Rose Johnstone, Marilyn Farquhar and Urinary Exosomes Uta Erdbrügger and Charles Blijdorp Mark Knepper
15:10 15:15 Session 1: uEV collection and storage Introduction to Collection work group Dylan Burger and Elena Martens-Uzunova Dylan Burger and Brian Byrd
15:15 15:35 Session 1: uEV collection and storage Home collection and storage Dylan Burger and Elena Martens-Uzunova Irene Bijnsdorp
15:35 15:40 Session 1: uEV collection and storage Introduction to Storage work group Dylan Burger and Elena Martens-Uzunova Elena Martens-Uzunova and Cristina Grande
15:40 16:00 Session 1: uEV collection and storage Imaging Flow Cytometry challenges classical NTA for the determination of uEV storage conditions and purification methods Dylan Burger and Elena Martens-Uzunova Marvin Droste
16:00 16:30 Session 1: uEV collection and storage Panel discussion “The Ideal Biobank” Dylan Burger and Elena Martens-Uzunova
Panelists: Irene Bijnsdorp, Marvin Droste, Maija Puhka, Mark Knepper, Guido Jenster
16:30 16:40 Break      
16:40 16:45 Session 2: uEV origin and analysis Introduction to uEV origin work group Alicia Llorente and Fabrice Lucien Alicia Llorente and Fabrice Lucien
16:45 17:05 Session 2: uEV origin and analysis Single and bulk uEV analysis Alicia Llorente and Fabrice Lucien Juan Manuel Falcon Perez
17:05 17:20 Abstract session: uEV origin and analysis A novel transgene mouse with an extravesicular EGFP tag enables affinity isolation of cell-specific extracellular vesicles Alicia Llorente and Fabrice Lucien Mikkel Noergaard
17:20 17:30 Abstract session: uEV origin and analysis Studying membrane organization of urothelial EVs by freeze-fracture electron microscopy Alicia Llorente and Fabrice Lucien Nataša Resnik
17:30 17:40 Abstract session: uEV origin and analysis EVQuant: high-throughput quantification and characterization of extracellular vesicle (sub)populations Alicia Llorente and Fabrice Lucien Martin van Royen
17:40 17:50 Break Break Break Break
17:50 18:00 Abstract session: uEV origin and analysis Density-based fractionation of urine to unravel the proteome landscape of extracellular vesicles in prostate cancer Elena Martens-Uzunova and Irene Bijnsdorp Bert Dhondt
18:00 18:10 Abstract session: uEV origin and analysis Urinary extracellular vesicle bound DNA for the detection of kidney allograft injury Elena Martens-Uzunova and Irene Bijnsdorp Ivana Sedej
18:10 18:20 Abstract session: uEV origin and analysis Robust, reproducible, and scalable workflow for isolation and transcriptomic profiling of vesicular and total extracellular urinary RNA during pregnancy Elena Martens-Uzunova and Irene Bijnsdorp Priyadarshini Pantham
18:20 18:50 Session 2: uEV origin and analysis Panel discussion “How to elucidate uEV origin?" Alicia Llorente and Luca Musante
Panelists: Fabrice Lucien, Juan Manuel Falcon Perez, Edit Buzas
           
Wednesday 16 February 16
14:30 14:35 Introduction Welcome Elena Martens-Uzunova & Alicia Llorente Elena Martens-Uzunova & Alicia Llorente
14:35 15:05 Keynote session Urinary extracellular vesicles as biomarker treasure chests for prostate cancer Elena Martens-Uzunova & Alicia Llorente Guido Jenster
15:05 15:20 Abstract session: Biomarkers Role of extracellular vesicle-vasorin in preeclampsia Brian Byrd and Inge Mertens Saravanakumar Murugesan
15:20 15:30 Abstract session: Biomarkers Identification of a Urine Extracellular Vesicle Signature to predict Renal Outcome after Kidney Transplant Brian Byrd and Inge Mertens Jacopo Burello
15:30 15:40 Abstract session: Biomarkers Identification of progressive biomarkers for diabetic nephropathy in large and small uEVs Brian Byrd and Inge Mertens Elisa Tonoli
15:40 15:50 Abstract session: Biomarkers The Proteomic Landscape of Urinary Extracellular Vesicles in Localized Prostate Cancer Brian Byrd and Inge Mertens Amanda Khoo
15:50 16:00 Abstract session: Biomarkers The urinary extracellular vesicle proteome of prostate cancer reveals distinct expression patterns and promising biomarkers Brian Byrd and Inge Mertens Ayse Erozenci
16:00 16:10 Abstract session: Biomarkers EphA2 on urinary extracellular vesicles is a novel diagnostic biomarker for bladder cancer Brian Byrd and Inge Mertens Eisuke Tomiyama
16:10 16:20 Break      
16:20 16:25 Session 3: Normalization Introduction to Normalization work group Charles Blijdorp and James Dear Charles Blijdorp
16:25 16:45 Session 3: Normalization Normalization Charles Blijdorp and James Dear Peter Yuen
16:45 17:15 Session 3: Normalization Panel discussion "To normalize or not to normalize" Charles Blijdorp and James Dear
Panelists: Harry Holthofer, Mat Luther, Peter Yuen, Inge Mertens
17:15 17:25 Break      
17:25 17:30 Session 4: Translation Introduction to Translation work group Uta Erdbrügger and Ewout Hoorn Uta Erdbrugger
17:30 17:50 Session 4: Translation Therapy and function Uta Erdbrügger and Ewout Hoorn Benedetta Bussolati
17:50 18:10 Session 4: Translation Roadblocks to clinical translation of uEV research Uta Erdbrügger and Ewout Hoorn James Dear
18:10 18:40 Session 4: Translation Panel discussion "Will uEVs replace kidney, bladder and prostate biopsies in the next decade?" Ken Witwer, Marvin Droste
Panelists: Uta Erdbrügger, Brian Byrd, James Dear, Benedetta Bussolati, Ewout Hoorn
18:40 18:50 Poster and Abstract Prizes  
Uta Erdbrügger; Alicia Llorente; Elena Martens-Uzunova; Charles Blijdorp; Dylan Burger
 
18:50 19:00 Wrap up and Farewell  
Uta Erdbrügger; Alicia Llorente; Elena Martens-Uzunova; Charles Blijdorp; Dylan Burger